fbpx
Connect with us

The Conversation

A young Black scientist discovered a pivotal leprosy treatment in the 1920s − but an older colleague took the credit

Published

on

theconversation.com – Mark M. Lambert, Assistant Professor of Behavioral Medicine, Medical Humanities, and Bioethics, Des Moines – 2024-04-12 07:24:22
The island of Molokai, where the Ball Method successfully treated leprosy sufferers.
Albert Pierce Taylor

Mark M. Lambert, Des Moines University

Hansen's disease, also called leprosy, is treatable – and that's partly thanks to a curious tree and the work of a pioneering young scientist in the 1920s. Centuries prior to her discovery, sufferers had no remedy for leprosy's debilitating symptoms or its social stigma.

This young scientist, Alice Ball, laid fundamental groundwork for the first effective leprosy treatment globally. But her legacy still prompts conversations about the marginalization of women and people of color in science today.

As a bioethicist and historian of medicine, I've studied Ball's contributions to medicine, and I'm pleased to see her receive increasing recognition for her work, especially on a disease that remains stigmatized.

Advertisement

Who was Alice Ball?

Alice Augusta Ball, born in Seattle, Washington, in 1892, became the first woman and first African American to earn a master's degree in science from the College of Hawaii in 1915, after completing her studies in pharmaceutical chemistry the year prior.

A black and white photo of Alice Ball, wearing a graduation cap and robes.
Alice Augusta Ball, who came up with The Ball Method, a treatment for leprosy that didn't come with unmanageable side effects.

After she finished her master's degree, the college hired her as a research chemist and instructor, and she became the first African American with that title in the chemistry department.

Impressed by her master's thesis on the chemistry of the kava plant, Dr. Harry Hollmann with the Leprosy Investigation Station of the U.S. Public Service in Hawaii recruited Ball. At the time, leprosy was a major public health issue in Hawaii.

now understand that leprosy, also called Hansen's disease, is minimally contagious. But in 1865, the fear and stigma associated with leprosy led authorities in Hawaii to implement a mandatory segregation policy, which ultimately isolated those with the disease on a remote peninsula on the island of Molokai. In 1910, over 600 leprosy sufferers were living in Molokai.

Advertisement

This policy overwhelmingly affected Native Hawaiians, who accounted for over 90% of all those exiled to Molokai.

The significance of chaulmoogra oil

Doctors had attempted to use nearly every remedy imaginable to treat leprosy, even experimenting with dangerous substances such as arsenic and strychnine. But the lone consistently effective treatment was chaulmoogra oil.

Chaulmoogra oil is derived from the seeds of the chaulmoogra tree. Health practitioners in India and Burma had been using this oil for centuries as a treatment for various skin diseases. But there were limitations with the treatment, and it had only marginal effects on leprosy.

The oil is very thick and sticky, which makes it hard to rub into the skin. The drug is also notoriously bitter, and who ingested it would often start vomiting. Some physicians experimented with injections of the oil, but this produced painful pustules.

Advertisement
A black and white photo of a woman poking a needle into a child's wrist, with two other women in the background watching.
Dr. Isabel Kerr, a European missionary, administering to a patient a chaulmoogra oil treatment in 1915, prior to the invention of the Ball Method.
George McGlashan Kerr, CC BY

The Ball Method

If researchers could harness chaulmoogra's curative potential without the nasty side effects, the tree's seeds could revolutionize leprosy treatment. So, Hollmann turned to Ball. In a 1922 article, Hollmann documents how the 23-year-old Ball discovered how to chemically adapt chaulmoogra into an injection that had none of the side effects.

The Ball Method, as Hollmann called her discovery, transformed chaulmoogra oil into the most effective treatment for leprosy until the introduction of sulfones in the late 1940s.

In 1920, the Ball Method successfully treated 78 patients in Honolulu. A year later, it treated 94 more, with the Public Health Service noting that the morale of all the patients drastically improved. For the first time, there was hope for a cure.

Tragically, Ball did not have the opportunity to revel in this achievement, as she passed away within a year at only 24, likely from exposure to chlorine gas in the lab.

Ball's legacy, lost and found

Ball's meant she didn't have the opportunity to publish her research. Arthur Dean, chair of the College of Hawaii's chemistry department, took over the .

Advertisement

Dean mass-produced the treatment and published a series of articles on chaulmoogra oil. He renamed Ball's method the “Dean Method,” and he never credited Ball for her work.

Ball's other colleagues did attempt to protect Ball's legacy. A 1920 article in the Journal of the American Medical Association praises the Ball Method, while Hollmann clearly credits Ball in his own 1922 article.

Ball is described at length in a 1922 article in volume 15, issue 5, of Current History, an academic publication on international affairs. That feature is excerpted in a June 1941 issue of Carter G. Woodson's “Negro History Bulletin,” referring to Ball's achievement and untimely death.

Joseph Dutton, a well-regarded religious volunteer at the leprosy settlements on Molokai, further referenced Ball's work in a 1932 memoir broadly published for a popular audience.

Advertisement

Historians such as Paul Wermager later prompted a modern reckoning with Ball's poor treatment by Dean and others, ensuring that Ball received proper credit for her work. Wermager's and others' work, the University of Hawaii honored Ball in 2000 with a bronze plaque, affixed to the last remaining chaulmoogra tree on campus.

In 2019, the London School of Hygiene and Tropical Medicine added Ball's name to the outside of its building. Ball's story was even in a 2020 short film, “The Ball Method.”

The Ball Method represents both a scientific achievement and a history of marginalization. A young woman of color pioneered a medical treatment for a highly stigmatizing disease that disproportionately affected an already disenfranchised Indigenous population.

The of Hawaii honored Ball by declaring Feb. 28 Alice Augusta Ball Day.

In 2022, then-Gov. David Ige declared Feb. 28 Alice Augusta Ball Day in Hawaii. It was only fitting that the ceremony took place on the Mānoa campus in the shade of the chaulmoogra tree.The Conversation

Mark M. Lambert, Assistant Professor of Behavioral Medicine, Medical Humanities, and Bioethics, Des Moines University

Advertisement

This article is republished from The Conversation under a Creative Commons license. Read the original article.

The Conversation

Teens see social media algorithms as accurate reflections of themselves, study finds

Published

on

theconversation.com – Nora McDonald, Assistant Professor of Information Technology, George Mason – 2024-04-29 07:26:15

say ‘for you' algorithms get them right.

Photo illustration by Spencer Platt/Getty Images

Nora McDonald, George Mason University

Social apps regularly present teens with algorithmically selected content often described as “for you,” suggesting, by implication, that the curated content is not just “for you” but also “about you” – a mirror reflecting important signals about the person you are.

Advertisement

All users of social media are exposed to these signals, but researchers understand that teens are at an especially malleable stage in the formation of personal identity. Scholars have begun to demonstrate that technology is generation-shaping effects, not merely in the way it influences cultural outlook, behavior and privacy, but also in the way it can shape personality among those brought up on social media.

The prevalence of the “for you” message raises important questions about the impact of these algorithms on how teens perceive themselves and see the world, and the subtle erosion of their privacy, which they accept in exchange for this view.

Teens like their algorithmic reflection

Inspired by these questions, my colleagues John Seberger and Afsaneh Razi of Drexel University and I asked: How are teens navigating this algorithmically generated milieu, and how do they recognize themselves in the mirror it ?

In our qualitative interview study of teens 13-17, we found that personalized algorithmic content does seem to present what teens interpret as a reliable mirror image of themselves, and that they very much like the experience of seeing that social media reflection.

Advertisement

Teens we spoke with say they prefer a social media completely customized for them, depicting what they agree with, what they want to see and, thus, who they are.

If I look up something that is important to me that will show up as one of the top posts [and] it'll show, like, people [like me] that are having a nice discussion.

It turns out that the teens we interviewed believe social media algorithms like TikTok's have gotten so good that they see the reflections of themselves in social media as quite accurate. So much so that teens are quick to attribute content inconsistencies with their self-image as anomalies – for instance, the result of inadvertent engagement with past content, or just a glitch.

At some point I saw something about that show, maybe on TikTok, and I interacted with it without actually realizing.

When personalized content is not agreeable or consistent with their self-image, the teens we interviewed say they scroll past it, hoping never to see it again. Even when these perceived anomalies take the form of extreme hypermasculine or “nasty” content, teens do not attribute this to anything about themselves specifically, nor do they claim to look for an explanation in their own behaviors. According to teens in our interviews, the social media mirror does not make them more self-reflective or challenge their sense of self.

One thing that surprised us was that while teens were aware that what they see in their “for you” feed is the product of their scrolling habits on social media platforms, they are largely unaware or unconcerned that that data captured across apps contributes to this self-image. Regardless, they don't see their “for you” feed as a challenge to their sense of self, much less a risk to their self-identity – nor, for that matter, any basis for concern at all.

Advertisement

The human brain continues to develop during adolescence.

Shaping identity

Research on identity has come a long way since sociologist Erving Goffman proposed the “presentation of self” in 1959. He posited that people manage their identities through social performance to maintain equilibrium between who they think they are and how others perceive them.

When Goffman first proposed his theory, there was no social media interface available to hold up a handy mirror of the self as experienced by others. People were obligated to create their own mosaic image, derived from multiple sources, encounters and impressions. In recent years, social media recommender algorithms have inserted themselves into what is now a three-way negotiation among self, public and social media algorithm.

“For you” offerings create a private-public through which teens can access what they feel is a largely accurate test of their self-image. At the same time, they say they can easily ignore it if it seems to disagree with that self-image.

The pact teens make with social media, exchanging personal data and relinquishing privacy to secure access to that algorithmic mirror, feels to them like a good bargain. They represent themselves as confidently able to tune out or scroll past recommended content that seems to contradict their sense of self, but research shows otherwise.

Advertisement

They have, in fact, proven themselves highly vulnerable to self-image distortion and other mental health problems based on social media algorithms explicitly designed to create and reward hypersensitivities, fixations and dysmorphia – a mental disorder where people fixate on their appearance.

Given what researchers know about the teen brain and that stage of social – and given what can reasonably be surmised about the malleability of self-image based on social feedback – teens are wrong to believe that they can scroll past the self-identity risks of algorithms.

U.S. Surgeon General Vivek Murthy discusses the harms teens face from social media.

Interventions

Part of the remedy could be to build new tools using artificial intelligence to detect unsafe interactions while also protecting privacy. Another approach is to teens reflect on these “data doubles” that they have constructed.

My colleagues and I are now exploring more deeply how teens experience algorithmic content and what types of interventions can help them reflect on it. We encourage researchers in our field to design ways to challenge the accuracy of algorithms and expose them as reflecting behavior and not being. Another part of the remedy may involve arming teens with tools to restrict access to their data, limiting cookies, having different search profiles and turning off location when using certain apps.

Advertisement

We believe that these are all steps that are likely to reduce the accuracy of algorithms, creating much-needed friction between algorithm and self, even if teens are not necessarily happy with the results.

Getting the kids involved

Recently, my colleagues and I conducted a Gen Z workshop with young people from Encode Justice, a global organization of high school and college students advocating for safe and equitable AI. The aim was to better understand how they are thinking about their lives under algorithms and AI. Gen Zers say they are concerned but also eager to be involved in shaping their future, including mitigating algorithm harms. Part of our workshop goal was to call attention to and foster the need for teen-driven investigations of algorithms and their effects.

What researchers are also confronting is that we don't actually know what it means to constantly negotiate identity with an algorithm. Many of us who study teens are too old to have grown up in an algorithmically moderated world. For the teens we study, there is no “before AI.”

I believe that it's perilous to ignore what algorithms are doing. The future for teens can be one in which society acknowledges the unique relationship between teens and social media. This means involving them in the solutions, while still providing guidance.The Conversation

Nora McDonald, Assistant Professor of Information Technology, George Mason University

Advertisement

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Continue Reading

The Conversation

Why are some people faster than others? 2 exercise scientists explain the secrets of running speed

Published

on

theconversation.com – Dawn P. Coe, Associate Professor of Exercise Science, of Tennessee – 2024-04-29 07:23:48

Jamaican sprinter Usain Bolt, in yellow, the world's speed record for humans.

AP Photo/David J. Phillip

Dawn P. Coe, University of Tennessee and Elizabeth (Kip) Webster, University of Tennessee

Curious Kids is a series for of all ages. If you have a question you'd like an expert to answer, send it to curiouskidsus@theconversation.com.

Advertisement

Why are some people faster than others? – Jon, age 14, Macon, Georgia


Usain Bolt, the world's fastest human, ran a 100-meter sprint at a speed of 23.35 miles per hour (37.57 kilometers per hour).

That's mind-blowingly fast for a human. It's about the same speed as cruising in a car through your neighborhood or in a school zone. It might not seem that fast when you're in the car, but for a person? Few runners in the world can even close.

There are several reasons why some people can run very fast while others tend to run more slowly. Genetics – the traits you inherit from your parents – play a role, but so do your choices and experiences.

As pediatric exercise scientists, we create and evaluate programs that help children be healthy. The exciting news is that while you have no control over your genetics, you can train to improve your speed.

Advertisement

Fast twitch, slow twitch

One major factor that influences your ability to run fast is the structure of your body, how your muscles work.

The human body has more than 600 muscles that work together, allowing you to move in different directions and at various speeds. These muscles are made up of groups of fibers. There are two main types: fast twitch and slow twitch.

Muscles have different mixes of these fiber types. For example, two muscles make up the calf: One is predominantly fast twitch – that's the gastrocnemius, used for sprinting and jumping. The other is mostly slow twitch – that's the soleus, used for walking and jogging.

Two women play soccer, one is in motion, clearly sprinting to kick the ball.

Speed and endurance are both important when you're playing soccer.

AP Photo/John Cowpland

Advertisement

Fast-twitch muscle fibers are larger and help your body move quickly and generate significant force. Sprinters tend to have an abundance of fast-twitch muscle fibers. However, this muscle fiber type also tires quickly, which limits how long you can run at top speed to relatively short distances.

Slow-twitch muscle fibers are smaller and help you run at slower speeds, but with greater endurance. Long-distance runners and competitive cyclists tend to have a lot of these muscles.

How much you have of each type of muscle fiber – fast twitch and slow twitch – is mostly determined by your genes, so you'll have to work with what you're born with when it comes to muscle types. But exercises can help train those muscles.

Your brain plays a big role

Physical ability isn't just about muscle. Your brain plays an important role, too.

Advertisement

Your skeletal muscles are controlled by your brain – you think about your actions and then execute the movements. For example, you can control how long your stride is, how your arms move, how your feet hit the ground and even the techniques you use to breathe.

You can teach your body to use the best running techniques. That includes proper posture, so your body is standing tall, and an economical stride, so your feet below you rather than too far out in front, where they can slow you down.

Five tips for running faster, from an Olympic sprinting coach.

You can also improve your running form by using your whole body, with your arms pumping in opposition to the legs, running on your toes and maximizing the time spent in flight phase with both feet off the ground. Using proper running techniques helps the muscles create more force and work together, which helps you run faster.

The more you practice an activity, the better you will get. As your ability to run fast increases, yourself to run even faster.

Advertisement

How to train to run faster – myth-busting!

You may have heard your friends chatting about ways to boost your speed or searched the internet for tips on getting faster. Time to bust some of those myths.

Myth 1: You have to run as fast as you can to train to be faster. That's false!

You don't have to run as fast as you can to get faster, and it actually helps to take short breaks to recover in between activities where you are sprinting.

Myth 2: You need to lift heavy weights to get faster. False!

Advertisement

Functional strength training involves performing exercises that help you get better at specific movements. They involve using either medium weights or just the resistance of your own body weight. Doing planks, lunges, step-ups or jump squats are great examples. These activities focus on the muscles that are instrumental during running.

Myth 3: You need to specialize in running early in to become a fast runner. False!

Picking one activity to focus on early in life may actually limit your ability to develop into a fast runner. Doing a variety of physical activities can help you develop new skills that improve your running. For example, the movements and endurance used in soccer may translate into the ability to run faster.

Myth 4: Training isn't fun. False!

Advertisement

Training programs can take many shapes and forms. You can play running with your friends, work on fast footwork using an agility ladder or create obstacle courses. There's nothing like a little healthy competition to motivate your training.

What's important is fun while training and participating in

activities that promote running speed on a regular basis.

So, whether you want to be the next Usain Bolt or you just want to win a race against your friend, remember that with a little bit of genetic luck and hard work, it may just be possible.The Conversation

Dawn P. Coe, Associate Professor of Exercise Science, University of Tennessee and Elizabeth (Kip) Webster, Associate Professor of Exercise Science, University of Tennessee

Advertisement

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Continue Reading

The Conversation

Ghosted, orbited, breadcrumbed? A psychotherapist breaks down some perils of digital dating and how to cope

Published

on

theconversation.com – Danielle Sukenik, Instructor of Psychiatry, of Colorado Anschutz Medical Campus – 2024-04-29 07:22:52

About a third of U.S. adults have looked for love online.

Maria Korneeva/Moment via Getty Images

Danielle Sukenik, University of Colorado Anschutz Medical Campus

Buzzwords describing the digital dating scene are all over social . Have you been ghosted? Is someone orbiting you? Are you being breadcrumbed? While these dating patterns may not be new, the words to describe them continue to evolve.

Advertisement

As a psychotherapist, I see firsthand the impact these experiences can have on mental . Given the sheer number of people using dating apps – 53% of American 18-to-29-year-olds and 37% of 30-to-49-year-olds – it's likely you have some first- or secondhand exposure to this world.

If you're curious about the latest psychological research on digital dating – and are looking for evidence-based strategies to cope – read on.

Ghosting and orbiting

Ghosting is a sudden disruption in a relationship without any explanation. The “ghoster” vanishes suddenly, often leaving the other person with questions. And orbiting? That's when someone ghosts but continues to follow the other person on social media by watching stories or occasionally engaging in their content. These behaviors are pretty common, and you might wonder about their impact.

A 2022 study the psychological consequences of being ghosted, orbited or rejected by asking 176 participants about one randomly assigned breakup strategy they had experienced out of these three. Then, participants completed a questionnaire rating various feelings about their breakup.

Advertisement

While feelings of rejection did not differ between the three breakup strategies – the end of a relationship hurts regardless – the results showed that ghosting led to stronger feelings of exclusion than being rejected outright. People in the ghosting category were also more likely to feel that their basic needs of belonging, self-esteem and control were threatened.

Being orbited, on the other hand, seemed to buffer victims partially from the emotional consequences of a breakup. Victims of orbiting, too, reported feeling higher levels of exclusion and threat to their basic needs than those who were rejected outright, but less than victims of ghosting did. Perhaps sporadic attention softens feelings of exclusion.

These findings are in line with other research. Understanding a breakup is important and helps individuals recover from the . With no explanation, the rejected individual may be left feeling confused and uncertain, sometimes with unhealed psychological wounds.

Orbiting may cause further ambiguity, as the orbiter's behavior suggests a mild residual interest in the other person. An individual might wonder if the other person is still attracted or might want to return to the relationship. For some people, this uncertainty can be harmful, while others find it easier to let go of a relationship if they're still receiving some level of digital attention.

Advertisement

A pair of studies in 2004 and 2005 showed people prefer receiving negative attention over being ignored entirely. In these role-playing experiments, those who experienced ostracism reported lower levels of belonging, control, meaningful existence and superiority than those who experienced an argument.

Sad woman reading her smart phone.

Being toyed with by a potential partner is especially damaging.

MementoJpeg/Moment/via Getty Images

Breadcrumbing

Breadcrumbing is when someone drops morsels of flirtatious attention to keep the other person interested, even though they have no intention of participating in a relationship. Some classic signs of breadcrumbing are not responding to messages for long periods of time, vague communication, and avoidance of discussions related to feelings. These patterns tend to boost the breadcrumber's ego, self-worth and sense of power.

For the person being breadcrumbed, it's a different story. A 2020 study of 626 adults found victims of breadcrumbing were significantly more likely to have feelings of loneliness, helplessness and less life satisfaction than victims of ghosting. Because people on the receiving end of breadcrumbing remain in limbo longer, they experience repeated feelings of exclusion and ostracism. The ongoing nature of breadcrumbing explains why it can have more negative effects on mental health.

Advertisement

Taking care of yourself

Given the prevalence of these behaviors, it's likely you've employed some of these dating tactics yourself. If so, I invite you to be mindful and think about how these patterns are serving you and consider your impact on others.

If you're also on the receiving end, here are some evidence-based strategies you can use to yourself and maintain a positive outlook about the dating scene.

Any time you have an experience, your mind is quick to create a narrative around what happened in order to make sense of it and create an illusion of control or safety. If you're not aware of the stories you tell yourself, you may find yourself incorrectly assigning blame or fault, which can to negative self-talk, anxiety and depression.

For example, rather than think, “I did something wrong to cause them to ghost me,” you could think, “Their to disengage from the relationship is more about them and how they relate to others than it is about me.” Being mindful of your cognitive patterns and practicing changing your narratives can keep online dating from wreaking havoc on your psyche.

Advertisement

Group of young people planting trees.

Living your values can have many .

miodrag ignjatovic/E+/via Getty Images

It's also crucial to take inventory of what's most important to you. Identifying your values will not only allow you to better match with like-minded people, but it will also improve your relationship with yourself. When your life aligns with what's important to you, you increase its meaning, purpose and overall well-being. In living this way, you might find looking for a relationship is less urgent, which could help you to better spot red flags or mismatches.

I also recommend varying the ways you connect to others to mitigate burnout. A healthy mix of apps and meeting people “in the wild” will often yield the best outcome and allow the dating adventure to remain exciting.The Conversation

Danielle Sukenik, Instructor of Psychiatry, University of Colorado Anschutz Medical Campus

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Advertisement
Continue Reading

News from the South

Trending