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‘Like a Russian Roulette’: US Military Firefighters Grapple With Unknowns of PFAS Exposure

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Patricia Kime and Hannah Norman, KFF Health
Thu, 07 Sep 2023 09:00:00 +0000

A U.S. military firefighter for 32 years, Kurt Rhodes trained and performed his duties with aqueous film forming foam, or AFFF — a highly effective fire suppressant that he never knew contained PFAS chemicals, now known to be harmful to human health.

New federal research links testicular cancer in U.S. service members to the “forever chemicals,” adding to a growing body of evidence of the dangers they pose. Rhodes lives in fear that he, like many of his colleagues, will get sick.

“It's kind of like a Russian roulette,” he said. “Are you going to get the cancers or are you going to be one of the lucky ones who doesn't?”

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The chemicals in the firefighting foam are suspected to have polluted more than 700 active and former military installations as well as thousands of towns across the U.S., potentially exposing millions of people to long-term health risks, say the scientists and public health experts who study the chemicals. The contamination was the result of industrial spills, dumping, and firefighting.

The new testicular cancer findings, as well as new requirements to fund PFAS testing in some communities, have firefighters like Rhodes on edge.

Many have sought recently developed blood serum tests to determine their cumulative levels of perfluoroalkyl and polyfluoroalkyl substances, or PFAS. But it's unclear what they should do with those test results, given there are no medical treatments to remove PFAS from the body.

“It is stressful, especially when you know there is a chance of cancer,” said former Air National Guard firefighter Jeffrey Warrick, noting he has a worrisome skin condition he believes was caused by PFAS exposure. It worsens in warm weather, he said, and “freaks me out.”

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In 2020, Congress required the Department of Defense to offer active-duty military firefighters blood tests for PFAS, thousands of compounds dubbed “forever chemicals” because they accumulate in the human body and don't break down in the . Some states followed suit or even preceded the federal legislative action.

Indiana passed a bill effective July 1 that establishes a biomonitoring pilot program to provide PFAS blood testing for 1,000 of the state's firefighters. New Hampshire requires insurers to cover PFAS blood tests, and a bill introduced in Maine this year would do the same.

But while the tests have been a major step forward in understanding the scope of the issue across the country, medical providers often aren't sure how to interpret the results.

Breaking the Code

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The National Academies of Sciences, Engineering, and Medicine issued preventive medical guidance last year for those whose test results confirm a level of PFAS chemicals in their blood meriting concern.

The national academies recommended that patients with readings between 2 and 20 nanograms per milliliter limit additional exposure and screen for high cholesterol, breast cancer, and, if pregnant, high blood pressure. At 20 ng/mL and above, the recommends further assessment.

But even with these published guidelines, finding knowledgeable about interpreting the blood test results and inferring the possible health effects of PFAS exposure can be slow going.

Kevin Ferrara, a former Air Force firefighter who now advocates for military personnel and firefighters, said they simply want their physicians to be more educated on PFAS contamination and its health consequences.

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“Firefighters really need to concentrate on their jobs, not ‘How do I decipher my blood tests?'” Ferrara said. “Physicians should have a basic understanding of PFAS, and they simply don't.”

To muddy matters further: With so many types of PFAS, not all of them show up in the blood tests. Some compounds manifest elsewhere, such as in organ tissue or other parts of the blood, said Neil McMillan, the International Association of Fire Fighters' director of science and research.

“These PFAS blood panels are complicated,” McMillan said. “The results you get back may not show the full picture of your body burden.”

Graham Peaslee, a of Notre Dame professor who studies PFAS, said he knows of seven civilian and military firefighters who have had a rare form of brain cancer, glioblastoma, three of whom resided in South Bend, Indiana.

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The aggressive disease has only sparsely been studied and its causes are not understood, although scientists suspect environmental exposures may be to blame.

“What's really interesting is it's [about] a one-in-a-million disease,” Peaslee said. “There aren't 7 million firefighters in this country. How was that possible?”

State Rep. Maureen Bauer, a Democrat who authored the Indiana PFAS testing bill and represents South Bend, said the program was inspired in part by those firefighters who died of brain cancer.

“Blood testing is providing one more useful bit of information,” Bauer said. “If you're exposed, but you don't know what your levels are, if you have fertility issues, high blood pressure, thyroid problems, that could all go back to your blood levels.”

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Guarding Against Risks

Ned Calonge, who is the associate dean for public health practice of the Colorado School of Public Health and co-authored the national academies' report, said that taking proactive measures in communities with known high exposure, such as among firefighters and military service members and their families who lived on bases, is particularly important.

“It depends on how much different states have paid attention to it,” Calonge said. “I wouldn't say that we've advanced very far in terms of clinician education in the area of the PFAS exposure.”

Congress passed legislation last year that gave medical benefits and disability compensation to federal firefighters who develop one or more of 16 health conditions within 10 years of service. The illnesses include 14 types of cancer, chronic obstructive pulmonary disease, and cardiovascular such as heart attack and stroke that occur within 24 hours of engaging in their jobs.

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But firefighters want to learn how to prevent these illnesses from taking hold. Because PFAS chemicals accumulate in the body, older people typically have higher levels than younger people. tend to have higher levels than women, which researchers attribute to menstruation helping eliminate the chemicals from the body.

Over time, if people limit exposure, PFAS levels in the blood can slowly drop as the chemicals are excreted. For example, PFOS, the legacy chemical found in AFFF that's no longer used, has a half-life in humans of 4.8 years. While researchers estimate that everyone has some level of PFAS in their bodies, Calonge said, people with levels above 20 ng/mL in their blood should particularly avoid additional exposure.

Although full avoidance may be nearly impossible — these chemicals can be found in nonstick cookware, industrial lubricants, cosmetics, and even food wrappers — those with high amounts of known exposure should consider filtering their drinking water and removing stain-resistant carpet, water-repellent clothing, and other PFAS-containing household goods from their homes, Calonge said.

Experts point to reverse osmosis filters under a kitchen sink or at the tap as the most effective way to remove PFAS from drinking water, but the systems can be expensive, putting them out of reach for some Americans. Some tabletop water filters seem pretty effective, too. The American National Standards Institute and NSF have certified water filters from 15 manufacturers for the reduction of select PFAS chemicals.

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Holding Out Hope

While there are no known treatments for the buildup of PFAS chemicals in one's body, an Australian study published last year found that firefighters with high levels of PFAS reduced their levels by 10% over a year when they donated blood every 12 weeks and by 30% if they donated plasma every six weeks.

Jeff Burgess, a University of Arizona Health Sciences researcher, seeks to duplicate the findings and take it a step further — determining whether a reduction in PFAS levels yields lower cardiovascular and cancer risk.

The plan is to enroll 1,500 firefighters in the study who will donate blood or plasma for a year, monitoring for DNA methylation cancer biomarkers.

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As for the ethics of letting firefighters with known PFAS contamination contribute to the nation's blood banks, Burgess noted that nearly everyone in the U.S. is thought to have some PFAS in their bodies and that, given chronic shortages, the need for donated blood outweighs the risks.

“From my perspective, the benefits of giving blood, even though it has some degree of PFAS in it, are much greater than the potential harm from the PFAS that people might receive because, again, blood products can be lifesaving,” Burgess said.

Citing the Australian study, Nicole Maul, director of relations for the American Red Cross, which manages standards and quality control for the blood banks, said further study is needed to determine whether donations by firefighters have any “clinical implications.”

“No study has shown a detrimental effect of such substances in blood for donors or recipients,” Maul said. “The Red Cross and the FDA work together to ensure the blood supply is as safe as possible, and individuals should not worry about the safety of donating or receiving blood.”

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A Department of Defense spokesperson said Aug. 29 that the Pentagon uses the Centers for Disease Control and Prevention's Agency for Toxic Substances and Disease Registry to guide its firefighter PFAS testing program and develop information it provides to personnel, including military physicians, on the potential health effects of PFAS.

“It is not possible yet to distinguish PFAS exposures by DoD personnel in their occupational setting from those they may experience from consumer products, so much of the information provided is general PFAS health effects information,” said Peter Graves, chief of media operations for the Defense Health Agency. “The DoD will occupational health provider fact sheets when ATSDR updates their PFAS clinical guidelines and develop or incorporate available PFAS modules for healthcare providers, as appropriate.”

Graves added that the Defense Department is interested in the outcomes of ongoing health studies by the Agency for Toxic Substances and Disease Registry as well as toxicology assessments by the Environmental Protection Agency and noted that the Pentagon supported the testicular cancer study by allowing use of the Department of Defense Serum Repository and including it in the Pentagon's Congressionally Directed Medical Research Programs.

CDMRP research projects are not requested by the Pentagon in its annual budget, but instead are supported by extra money that Congress gives the department to manage research projects that members deem necessary to advance medical science and promote the health of the armed forces.

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Rhodes, the veteran military firefighter, said he has high hopes for the University of Arizona research and would like to see more studies done on reducing PFAS exposure as well as the illnesses linked to PFAS. He also wants Congress to extend the health and disability benefits for a lifetime for those illnesses.

“I put my life on the line for 30 years for people I didn't know, and I did it willingly,” he said. “That is every firefighter's mindset. Now we are asking for a little bit. There's something out there killing us. Keep researching and don't give us pushback when we want testing. Make it easier for us.”

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By: Patricia Kime and Hannah Norman, KFF Health News
Title: ‘Like a Russian Roulette': US Military Firefighters Grapple With Unknowns of PFAS Exposure
Sourced From: kffhealthnews.org/news/article/pfas-forever-chemicals-exposure-military-firefighters-unknowns/
Published Date: Thu, 07 Sep 2023 09:00:00 +0000

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The Lure of Specialty Medicine Pulls Nurse Practitioners From Primary Care

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Michelle Andrews
Fri, 17 May 2024 09:00:00 +0000

For many , seeing a nurse practitioner has become a routine part of primary care, in which these “NPs” often perform the same tasks that patients have relied on doctors for.

But NPs in specialty care? That's not routine, at least not yet. Increasingly, though, nurse practitioners and physician assistants are joining cardiology, dermatology, and other specialty practices, broadening their skills and increasing their income.

This worries some people who track the workforce, because current trends suggest primary care, which has counted on nurse practitioners to backstop physician shortages, soon might not be able to rely on them to the same extent.

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“They're succumbing to the same challenges that we have with physicians,” said Atul Grover, executive director of the Research and Action Institute at the Association of American Medical Colleges. The rates NPs can command in a specialty practice “are quite a bit higher” than practice salaries in primary care, he said.

When nurse practitioner programs began to proliferate in the 1970s, “at first it looked great, producing all these nurse practitioners that go to work with primary care physicians,” said Yalda Jabbarpour, director of the American Academy of Physicians' Robert Graham Center for Policy Studies. “But now only 30% are going into primary care.”

Jabbarpour was referring to the 2024 primary care scorecard by the Milbank Memorial Fund, which found that from 2016 to 2021 the proportion of nurse practitioners who worked in primary care practices hovered between 32% and 34%, even though their numbers grew rapidly. The proportion of physician assistants, also known as physician associates, in primary care ranged from 27% to 30%, the study found.

Both nurse practitioners and physician assistants are advanced practice clinicians who, in addition to graduate degrees, must complete distinct education, , and certification steps. NPs can practice without a doctor's supervision in more than two dozen states, while PAs have similar independence in only a handful of states.

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About 88% of nurse practitioners are certified in an area of primary care, according to the American Association of Nurse Practitioners. But it is difficult to track exactly how many work in primary care or in specialty practices. Unlike physicians, they're generally not required to be endorsed by a national standard-setting body to practice in specialties like oncology or cardiology, for example. The AANP declined to answer questions about its annual workforce survey or the extent to which primary care NPs are moving toward specialties.

Though data tracking the change is sparse, specialty practices are adding these advanced practice clinicians at almost the same rate as primary care practices, according to frequently cited research published in 2018.

The clearest evidence of the shift: From 2008 to 2016, there was a 22% increase in the number of specialty practices that employed nurse practitioners and physician assistants, according to that study. The increase in the number of primary care practices that employed these professionals was 24%.

Once more, the most recent projections by the Association of American Medical Colleges predict a dearth of at least 20,200 primary care physicians by 2036. There will also be a shortfall of non-primary care specialists, a deficiency of at least 10,100 surgical physicians and up to 25,000 physicians in other specialties.

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When it to the actual work performed, the lines between primary and specialty care are often blurred, said Candice Chen, associate professor of health policy and management at George Washington .

“You might be a nurse practitioner working in a gastroenterology clinic or cardiology clinic, but the scope of what you do is starting to overlap with primary care,” she said.

Nurse practitioners' salaries vary widely by location, type of facility, and experience. Still, according to data from recruiter AMN Healthcare Physician Solutions, formerly known as Merritt Hawkins, the total annual average starting compensation, including signing bonus, for nurse practitioners and physician assistants in specialty practice was $172,544 in the year that ended March 31, slightly higher than the $166,544 for those in primary care.

According to forecasts from the federal Bureau of Labor Statistics, nurse practitioner jobs will increase faster than jobs in almost any other occupation in the decade leading up to 2032, growing by 123,600 jobs or 45%. (Wind turbine service technician is the only other occupation projected to grow as fast.) The growth rate for physician assistants is also much faster than average, at 27%. There are more than twice as many nurse practitioners as physician assistants, however: 323,900 versus 148,000, in 2022.

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To Grover, of the AAMC, numbers like this signal that there will probably be enough NPs, PAs, and physicians to meet primary care needs. At the same time, “expect more NPs and PAs to also flow out into other specialties,” he said.

When Pamela Ograbisz started working as a registered nurse 27 years ago, she worked in a cardiothoracic intensive care unit. After she became a family nurse practitioner a few years later, she found a job with a similar specialty practice, which trained her to take on a bigger role, first running their outpatient clinic, then working on the floor, and later in the intensive care unit.

If nurse practitioners want to specialize, often “the doctors mentor them just like they would with a physician residency,” said Ograbisz, now vice president of clinical operations at temporary placement recruiter LocumTenens.com.

If physician assistants want to specialize, they also can do so through mentoring, or they can “certificates of added qualifications” in 10 specialties to demonstrate their expertise. Most employers don't “encourage or require” these certificates, however, said Jennifer Orozco, chief medical officer at the American Academy of Physician Associates.

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There are a number of training programs for family nurse practitioners who want to develop skills in other areas.

Raina Hoebelheinrich, 40, a family nurse practitioner at a regional medical center in Yankton, South Dakota, recently enrolled in a three-semester post-master's endocrinology training program at Mount Marty University. She lives on a farm in nearby northeastern Nebraska with her husband and five sons.

Hoebelheinrich's new skills could be helpful in her current hospital job, in which she sees a lot of patients with acute diabetes, or in a clinic setting like the one in Sioux Falls, South Dakota, where she is doing her clinical endocrinology training.

Lack of access to endocrinology care in rural areas is a real problem, and many people may travel hundreds of miles to see a specialist.

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“There aren't a lot of options,” she said.

——————————
By: Michelle Andrews
Title: The Lure of Specialty Medicine Pulls Nurse Practitioners From Primary Care
Sourced From: kffhealthnews.org/news/article/nurse-practitioners-trend-primary-care-specialties/
Published Date: Fri, 17 May 2024 09:00:00 +0000

Did you miss our previous article…
https://www.biloxinewsevents.com/clean-needles-save-lives-in-some-states-they-might-not-be-legal/

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Clean Needles Save Lives. In Some States, They Might Not Be Legal.

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Ed Mahon, Spotlight PA and Sarah Boden, WESA
Fri, 17 May 2024 09:00:00 +0000

Kim Botteicher hardly thinks of herself as a criminal.

On the main floor of a former Catholic church in Bolivar, Pennsylvania, Botteicher runs a flower shop and cafe.

In the former church's basement, she also operates a nonprofit organization focused on helping people caught up in the drug epidemic get back on their feet.

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The nonprofit, FAVOR ~ Western PA, sits in a rural pocket of the Allegheny Mountains east of Pittsburgh. Her organization's home county of Westmoreland has seen roughly 100 or more drug overdose deaths each year for the past several years, the majority involving fentanyl.

Thousands more in the region have been touched by the scourge of addiction, which is where Botteicher comes in.

She helps people find housing, jobs, and , and works with families by running groups and explaining that substance use disorder is a disease, not a moral failing.

But she has also talked publicly about how she has made sterile syringes available to people who use drugs.

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“When that person comes in the door,” she said, “if they are covered with abscesses because they have been using needles that are dirty, or they've been sharing needles — maybe they've got hep C — we see that as, ‘OK, this is our first step.'”

Studies have identified public health benefits associated with syringe exchange services. The Centers for Disease Control and Prevention says these programs reduce HIV and hepatitis C infections, and that new users of the programs are more likely to enter drug treatment and more likely to stop using drugs than nonparticipants.

This harm-reduction strategy is supported by leading health groups, such as the American Medical Association, the World Health Organization, and the International AIDS Society.

But providing clean syringes could put Botteicher in legal danger. Under Pennsylvania law, it's a misdemeanor to distribute drug paraphernalia. The state's definition includes hypodermic syringes, needles, and other objects used for injecting banned drugs. Pennsylvania is one of 12 states that do not implicitly or explicitly authorize syringe services programs through statute or regulation, according to a 2023 analysis. A few of those states, but not Pennsylvania, either don't have a drug paraphernalia law or don't include syringes in it.

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Those working on the front lines of the opioid epidemic, like Botteicher, say a reexamination of Pennsylvania's law is long overdue.

There's an urgency to the issue as well: Billions of dollars have begun flowing into Pennsylvania and other states from legal settlements with companies over their role in the opioid epidemic, and syringe services are among the eligible interventions that could be supported by that money.

The opioid settlements reached between drug companies and distributors and a coalition of state attorneys general included a list of recommendations for spending the money. Expanding syringe services is listed as one of the core strategies.

But in Pennsylvania, where 5,158 people died from a drug overdose in 2022, the state's drug paraphernalia law stands in the way.

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Concerns over Botteicher's work with syringe services recently led Westmoreland County officials to cancel an allocation of $150,000 in opioid settlement funds they had previously approved for her organization. County Commissioner Douglas Chew defended the by saying the county “is very risk averse.”

Botteicher said her organization had planned to use the money to hire additional recovery specialists, not on syringes. Supporters of syringe services point to the cancellation of funding as evidence of the need to change state law, especially given the recommendations of settlement documents.

“It's just a huge inconsistency,” said Zoe Soslow, who leads overdose prevention work in Pennsylvania for the public health organization Vital Strategies. “It's causing a lot of confusion.”

Though sterile syringes can be purchased from pharmacies without a prescription, handing out free ones to make drug use safer is generally considered illegal — or at least in a legal gray area — in most of the state. In Pennsylvania's two largest cities, Philadelphia and Pittsburgh, officials have used local health powers to provide legal protection to people who operate syringe services programs.

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Even so, in Philadelphia, Mayor Cherelle Parker, who took office in January, has made it clear she opposes using opioid settlement money, or any funds, to pay for the distribution of clean needles, The Philadelphia Inquirer has reported. Parker's position a major shift in that city's approach to the opioid epidemic.

On the other side of the state, opioid settlement funds have had a big effect for Prevention Point Pittsburgh, a harm reduction organization. Allegheny County reported spending or committing $325,000 in settlement money as of the end of last year to support the organization's work with sterile syringes and other supplies for safer drug use.

“It was absolutely incredible to not have to fundraise every single dollar for the supplies that go out,” said Prevention Point's executive director, Aaron Arnold. “It takes a lot of energy. It pulls away from actual delivery of services when you're constantly having to find out, ‘Do we have enough money to even purchase the supplies that we want to distribute?'”

In parts of Pennsylvania that lack these legal protections, people sometimes operate underground syringe programs.

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The Pennsylvania law banning drug paraphernalia was never intended to apply to syringe services, according to Scott Burris, director of the Center for Public Health Law Research at Temple University. But there have not been court cases in Pennsylvania to clarify the issue, and the failure of the legislature to act creates a chilling effect, he said.

Carla Sofronski, executive director of the Pennsylvania Harm Reduction Network, said she was not aware of anyone having faced criminal charges for operating syringe services in the state, but she noted the threat hangs over people who do and that they are taking a “great risk.”

In 2016, the CDC flagged three Pennsylvania counties — Cambria, Crawford, and Luzerne — among 220 counties nationwide in an assessment of communities potentially vulnerable to the rapid spread of HIV and to new or continuing high rates of hepatitis C infections among people who inject drugs.

Kate Favata, a resident of Luzerne County, said she started using heroin in her late teens and wouldn't be alive today if it weren't for the support and community she found at a syringe services program in Philadelphia.

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“It kind of just made me feel like I was in a safe . And I don't really know if there was like a come-to-God moment or come-to-Jesus moment,” she said. “I just wanted better.”

Favata is now in long-term recovery and works for a medication-assisted treatment program.

At clinics in Cambria and Somerset Counties, Highlands Health provides free or low-cost medical care. Despite the legal risk, the organization has operated a syringe program for several years, while also testing patients for infectious diseases, distributing overdose reversal medication, and offering recovery options.

Rosalie Danchanko, Highlands Health's executive director, said she hopes opioid settlement money can eventually support her organization.

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“Why shouldn't that wealth be spread around for all organizations that are working with people affected by the opioid problem?” she asked.

In February, legislation to legalize syringe services in Pennsylvania was approved by a committee and has moved forward. The administration of Gov. Josh Shapiro, a Democrat, supports the legislation. But it faces an uncertain future in the full legislature, in which Democrats have a narrow majority in the House and control the Senate.

One of the bill's lead sponsors, state Rep. Jim Struzzi, hasn't always supported syringe services. But the Republican from western Pennsylvania said that since his brother died from a drug overdose in 2014, he has come to better understand the nature of addiction.

In the committee vote, nearly all of Struzzi's Republican colleagues opposed the bill. State Rep. Paul Schemel said authorizing the “very instrumentality of abuse” crossed a line for him and “would be enabling an evil.”

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After the vote, Struzzi said he wanted to build more bipartisan support. He noted that some of his own skepticism about the programs eased only after he visited Prevention Point Pittsburgh and saw how workers do more than just hand out syringes. These types of programs connect people to resources — overdose reversal medication, wound care, substance use treatment — that can save lives and to recovery.

“A lot of these people are … desperate. They're alone. They're afraid. And these programs bring them into someone who cares,” Struzzi said. “And that, to me, is a step in the right direction.”

At her nonprofit in western Pennsylvania, Botteicher is hoping lawmakers take action.

“If it's something that's going to help someone, then why is it illegal?” she said. “It just doesn't make any sense to me.”

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This story was co-reported by WESA Public Radio and Spotlight PA, an independent, nonpartisan, and nonprofit newsroom producing investigative and public-service journalism that holds power to account and drives positive change in Pennsylvania.

KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.

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This story can be republished for free (details).

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By: Ed Mahon, Spotlight PA and Sarah Boden, WESA
Title: Clean Needles Save Lives. In Some States, They Might Not Be Legal.
Sourced From: kffhealthnews.org/news/article/clean-needles-syringe-services-programs-legal-gray-area-risk-pennsylvania/
Published Date: Fri, 17 May 2024 09:00:00 +0000

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Watch: John Oliver Dishes on KFF Health News’ Opioid Settlements Series

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Fri, 17 May 2024 09:00:00 +0000

Opioid manufacturers, distributors, and retailers are paying tens of billions of dollars in restitution to settle lawsuits related to their role in the nation's overdose epidemic. A recent of “Last Tonight With John Oliver” examined how that money is being spent by and local governments across the United States.

The segment from the KFF Health “Payback: Tracking the Opioid Settlement Cash.” You can learn more about the issue and read our collection of articles by Aneri Pattani here.

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Title: Watch: John Oliver Dishes on KFF News' Opioid Settlements Series
Sourced From: kffhealthnews.org/news/article/watch-john-oliver-kff-health-news-payback-opioid-settlements-series/
Published Date: Fri, 17 May 2024 09:00:00 +0000

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