by Shirley Wimbish Gray, Mississippi Today
May 2, 2025

Editor’s note: This essay is part of Mississippi Today Ideas, a platform for thoughtful Mississippians to share fact-based ideas about our state’s past, present and future. You can read more about the section here.

Given recent policy changes threatening the future of medical research and news of Mississippi’s falling childhood vaccination rates, I fear we are ignoring lessons learned the hard way. 

One of those lessons occurred during a yellow fever outbreak in the summer of 1898 when a community of honest citizens in Orwood, then a hamlet in southwest Lafayette County, helped a team of physicians change the direction of public health for Mississippi and the rest of the country.

I first heard about their story listening to a documentary about yellow fever with my husband, a virologist, who teaches at the University of Mississippi. The video mentioned an unnamed doctor in Mississippi who had advanced a theory linking mosquitoes and yellow fever.

The story I uncovered models the honesty and trust in medical science we need today to keep our families and communities healthy. 

***

Yellow fever was a problem in the South throughout the 1800s. Its initial symptoms — fever, body aches and severe headache — were followed by jaundice and in some cases internal bleeding leading to death. The jaundice left the skin tinged with yellow, thus the name “yellow fever.”  

In early August 1898, a young woman named Sallie Wilson Gray (no relation to the author) developed chills and a fever while visiting at her uncle’s home in Taylor. Her uncle immediately sent her home to be cared for by her family in Orwood, about 10 miles away.  

Days later, Sallie’s uncle in Taylor died from what proved to be yellow fever. Family members wiped black vomit, a sign of internal bleeding, from his body as he lay in his coffin. 

Sallie had now brought the same illness home to Orwood. 

***

I learned about yellow fever in seventh grade when we studied the 1878 yellow fever epidemic, the worst to strike the Mississippi River Valley. That year, Mississippi reported almost 17,000 cases and more than 4,000 deaths. I didn’t realize, though, how yellow fever continued to appear year after year. 

Physicians had a basic understanding of bacteria after the Civil War, but they didn’t recognize viruses, which proved to be the cause of yellow fever, until later in the 1900s. One popular theory suggested yellow fever spread on fomites—inanimate surfaces—like bedding, clothing and furniture. Panic often followed news of a yellow fever outbreak. Health officials established quarantines, closed roads, river ports and train stations, hoping to curb the spread of infections. 

The fear of what was not known then about yellow fever reminded me of the early days of the COVID pandemic when fear spread through rumors and unconfirmed anecdotes on social media. 

***

Sallie’s sisters and brothers in Orwood soon developed the same symptoms as Sallie. By September, 30-plus people in Taylor and Orwood showed signs of the disease and new cases were reported outside the local area. In response, three interstate railroads shut down and Memphis halted train traffic coming into the city. In Starkville, the president of Mississippi A&M (now Mississippi State University) posted a column of guards along its roads. In mid-October, officials placed all of Mississippi under quarantine as thousands fled the state. 

Months earlier, the governor of Mississippi, recognizing the heavy toll yellow fever often brought to his state, had sent a team of Board of Health physicians to Cuba, the center for yellow fever research. There the group met with Dr. Walter Reed, the Army physician directing the American research interests on the island. Reed pursued a theory that mosquitos transmitted the disease, but his experiments to establish that link repeatedly failed. The Mississippi team, including Dr. Henry Gant, a Water Valley doctor, returned home, still hopeful that science could soon solve the yellow fever mystery.

Gant immediately responded when he learned about the outbreak in Taylor. So did Dr. Henry Rose Carter, a field epidemiologist who served as the quarantine officer at Ship Island and who investigated yellow fever outbreaks throughout the South. 

Committed to the same rigorous scientific process that epidemiologists use today, Carter looked for patterns in how diseases spread within clusters of people. With yellow fever, he needed to identify the first person to develop the disease in a specific area and then trace everybody and everything that the person came into contact with.  

Over and over again, unreliable sources or conflicting pieces of data prevented Carter from finding a pattern. People, suspicious of government intervention and scared of the consequences of yellow fever, often distorted the truth. 

Fortunately for us today, the people of Orwood proved to be different. The people, Carter wrote, were “honest enough to tell the truth” and cooperated with efforts to trace the infection of each case.

Working with Carter, Gant moved from house to house in Orwood, instructing families to quarantine at home, though their natural inclination was to care for their neighbors. He also questioned each person, recording data for Gant’s analysis. 

Unlike diseases that produce low-grade fevers, an abrupt and high fever often characterizes a case of yellow fever. For that reason, many of the people Gant interviewed reported the day their infections started and also the time their fevers ignited: Mr. G. W. McMillan, sickened on Aug. 29 at noon.  Mrs. Rogers, Sept. 4, 10:00 am. 

Collecting this detailed information about time proved essential for Carter’s study and he cheered Gant’s ability to gather such reliable data. “A greater tribute to the good faith of the community, or to its confidence in Dr. Gant, can scarcely be given,” he wrote. 

Studying the Orwood data, Carter recognized a consistent time interval between cases, about two weeks between the first case and the development of secondary cases. This meant that the infection did not immediately spread from person-to-person but required time to incubate. He called this the period of extrinsic incubation.

I’ve read Carter’s scientific report with the results of the Orwood study, the same report that persuaded Walter Reed to alter his experimental process. Waiting 10-14 days before introducing infected mosquitos to healthy volunteers, Reed successfully demonstrated the transmission of yellow fever from mosquito to human. 

With the development of mosquito control procedures, the fever soon vanished in the U.S. and Caribbean. Today a vaccine can protect those travelling or living where the disease remains a threat.

***

Sallie and her siblings were among the lucky, surviving their infections with only lingering weakness and fatigue. When frosts fell in north Mississippi in early November 1898, the number of fever cases quickly fell. In total, officials confirmed 2,478 cases across the state. Those who died totaled 114.

Reed later acknowledged that the “work in Mississippi did more to impress me with the importance of an intermediate host in yellow fever than everything else put together.”  

***

My husband and I drove from our home in Oxford to Taylor and then Orwood on a hot muggy day in August, probably experiencing the same weather conditions as Sallie. Orwood is a ghost town today, but we found the cemetery where Sallie’s uncle is buried, adjacent to the wood-planked Presbyterian Church that still stands. 

Walking those grounds emphasized for me what the neighbors who once lived in Orwood taught us. Honesty and rigorous scientific inquiry — and not political rhetoric or unproven claims — are the tools we must trust to combat disease and dispel fear.

Bio: Shirley Wimbish Gray lives in Oxford. A retired writing instructor and science editor, she writes about what is often overlooked or forgotten, particularly in the American South. Her recent essays have appeared in Earth Island, Brevity Blog and Persimmon Tree. 

This article first appeared on Mississippi Today and is republished here under a Creative Commons Attribution-NoDerivatives 4.0 International License.

The post Ghost town of Orwood residents provide lessons for today by working with scientists in 1800s to combat yellow fever appeared first on mississippitoday.org

Note: The following A.I. based commentary is not part of the original article, reproduced above, but is offered in the hopes that it will promote greater media literacy and critical thinking, by making any potential bias more visible to the reader –Staff Editor.

Political Bias Rating: Centrist

This article does not present a clear ideological stance but rather focuses on a historical account of a yellow fever outbreak in 1898 and its connection to scientific advancements. The content emphasizes the importance of honesty, scientific inquiry, and collaboration, contrasting it with political rhetoric and unproven claims. The mention of contemporary issues, like Mississippi’s falling childhood vaccination rates and recent policy changes affecting medical research, introduces a subtle critique of current trends in public health. However, the tone remains balanced, and the piece refrains from offering a partisan viewpoint, focusing instead on lessons learned from history and the value of scientific rigor. The discussion of current events is presented more as a concern for public health rather than a partisan critique.

by Jerry Mitchell, Mississippi Today
May 2, 2025

May 2, 1964

Henry Hezekiah Dee and Charles Eddie Moore, two 19-year-old Black Americans, were simply trying to get a ride back home. Instead, Klansmen abducted them, took them to the Homochitto National Forest, where they beat the pair and then drowned them in the Mississippi River. 

When their bodies were found in an old part of the river, FBI agents initially thought they had found the bodies of three missing civil rights workers, James Chaney, Andrew Goodman and Michael Schwerner. 

Thanks to the work of Moore’s brother, Thomas, and Canadian filmmaker David Ridgen, federal authorities reopened the case in 2005. Two years later, a federal jury convicted James Ford Seale. He received three life sentences and died in prison. 

Ridgen did a podcast on the case for the CBC series, “Somebody Knows Something.”

This article first appeared on Mississippi Today and is republished here under a Creative Commons Attribution-NoDerivatives 4.0 International License.

The post On this day in 1964, Klan killed Henry Dee and Charles Moore appeared first on mississippitoday.org

Note: The following A.I. based commentary is not part of the original article, reproduced above, but is offered in the hopes that it will promote greater media literacy and critical thinking, by making any potential bias more visible to the reader –Staff Editor.

Political Bias Rating: Centrist

This article presents historical facts about the 1964 kidnapping and murder of two Black Americans by Klansmen. It provides an account of the tragic event, recounting the abduction, the subsequent investigation, and the eventual conviction of one of the perpetrators. The article sticks to reporting the details of the case, including the efforts of Thomas Moore and filmmaker David Ridgen to reopen the case and bring justice. While the subject matter is deeply tied to civil rights, the tone of the article remains neutral, focusing on factual events without pushing a particular ideological stance. The language used is factual and matter-of-fact, presenting the events as they happened rather than offering opinion or judgment, making the content centrist in its approach.

by Eric J. Shelton, Mississippi Today
April 30, 2025

The University of Mississippi Medical Center’s Department of Otolaryngology-Head and Neck Surgery hosted a free oral, head, and neck cancer screening Wednesday at the Jackson Medical Mall as part of Oral, Head and Neck Cancer Awareness Week.

The event featured quick, noninvasive screenings aimed at catching cancer early — when treatment is most effective. Onyx Care provided free HPV vaccinations, while the ACT Center for Tobacco Treatment, Education, and Research offered resources on smoking cessation and free services.

“These screenings take about 10 minutes and can save lives,” said Dr. Gina Jefferson, head and neck surgical oncologist at UMMC. “The earlier a cancer is diagnosed, the better chance we have of curing it.”

Tobacco and alcohol use remain major risk factors for these cancers. However, physicians say an increasing number of cases are linked to HPV, especially among younger adults with no history of smoking or drinking. Dentists are often the first to spot early signs, which can include persistent sores, lumps in the neck, or difficulty swallowing.

Oral, head and neck cancers are among the most common globally. When found early, survival rates can exceed 80 percent.

This article first appeared on Mississippi Today and is republished here under a Creative Commons Attribution-NoDerivatives 4.0 International License.

The post UMMC holds free cancer screenings appeared first on mississippitoday.org

Note: The following A.I. based commentary is not part of the original article, reproduced above, but is offered in the hopes that it will promote greater media literacy and critical thinking, by making any potential bias more visible to the reader –Staff Editor.

Political Bias Rating: Centrist

This article presents factual information about a free cancer screening event without showing a clear ideological stance. It primarily focuses on the health benefits of early cancer detection and the availability of free resources, such as HPV vaccinations and smoking cessation support. The language used is neutral and the content is centered around public health education rather than promoting a political viewpoint. The inclusion of factual statistics, such as survival rates and risk factors, adds to its informative and objective tone. There are no signs of bias or advocacy for a particular political agenda, making this a centrist piece.