SUMMARY: The Trump administration imposed new restrictions on flights from Mexico, citing violations of a U.S.-Mexico aviation agreement. Transportation Secretary Sean Duffy criticized Mexico for forcing airlines to use a less accessible airport, claiming it favored domestic carriers. In response, Mexican airlines must now seek U.S. approval for all flights. The move also threatens the Delta-Aeromexico partnership, which has existed since 2016 and supports \$800 million in annual savings. Delta warned the breakup would hurt consumers and jobs. The order to end the partnership won’t take effect until October, giving both airlines time to contest the decision.

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SUMMARY: Sarepta Therapeutics refused the FDA’s request to halt shipments of its gene therapy Elevidys after three patient deaths linked to liver injury. The FDA’s unusual move followed concerns over safety, particularly for older Duchenne muscular dystrophy patients. Elevidys, the first U.S.-approved gene therapy for this fatal muscle-wasting disease, received accelerated approval despite initial doubts about effectiveness. Sarepta halted sales for older patients but plans to keep the drug available for younger ones. The company confirmed a third death in an experimental trial, prompting the FDA to pause that study. Sarepta faces criticism over transparency and has recently cut 500 jobs amid plummeting stock value.

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SUMMARY: Three members of the Los Angeles County Sheriff’s Department’s arson and explosives unit were killed in a blast at the Biscailuz Training Facility. Authorities are investigating whether the explosion was a training accident. These units handle bomb disposal, arson investigations, and threat prevention. Training is rigorous, often through FBI and ATF programs, and includes real-life simulations. Smaller agencies often rely on larger departments for such expertise. Explosives training is inherently dangerous due to unpredictable variables. Past incidents, including a 2021 fireworks explosion in Los Angeles, highlight the risks faced by these specialized teams. The fallen detectives were highly trained and experienced.

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